Research Methods

Introduction to Bias, Confounding, and Missing Data

This course equips learners with the tools to identify and manage threats to research validity. Across six lessons, participants explore the core forms of bias and confounding, work through real-world case studies on selecting and controlling for confounders, distinguish effect modification from confounding, apply stratified analysis techniques in statistical software, and learn best practices for diagnosing and handling missing data.

5 lessons 32 steps English Certificate available
Course overview

Spot the errors. Adjust the analysis. Trust your results.

This course equips learners with the tools to identify and manage threats to research validity. Across six lessons, participants explore the core forms of bias and confounding, work through real-world case studies on selecting and controlling for confounders, distinguish effect modification from confounding, apply stratified analysis techniques in statistical software, and learn best practices for diagnosing and handling missing data.

01
Compare types of bias and confounding

Distinguish selection bias, information bias, and confounding, and understand how each distorts the true relationship between exposure and outcome.

02
Detect and adjust for confounders in real analyses

Apply directed acyclic graphs, stratified analysis, and propensity score methods to identify confounders and control for them appropriately.

03
Recognize effect modification and interpret it correctly

Distinguish genuine subgroup variation (effect modification) from bias, and learn when to report stratified estimates instead of a single crude result.

04
Diagnose and manage missing data

Identify the causes and types of missingness (MCAR, MAR, MNAR), and apply appropriate handling methods from complete case analysis to multiple imputation, to reduce bias and preserve statistical power.

Learning path

Know exactly what to do next.

Lessons are organized into short, completable steps so learners can make progress even during a busy clinical or research week.

Designed for completion

Small supports that keep learners moving.

Short lessons

Clear steps make the course easier to finish alongside clinical and research duties.

Field-ready tools

Use course examples and checklists to apply learning in real research workflows.

Bilingual pathway

English and French course support helps teams learn across language contexts.

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